Buy Rapamune (Sirolimus) from Maple Leaf Medications.

What is Rapamune used for?

Rapamune, with the generic name sirolimus, is an oral medication used to prevent organ rejection in patients 13 and older who are undergoing renal transplantation. It is also indicated to treat a certain lung disease called lymphangioleiomyomatosis or LAM.

This is available in Rapamune 2 mg and 1 mg tablet form.

How does Rapamune work?

This mammalian target of rapamycin (mTOR) inhibitor immunosuppressant works by inhibiting the activation and proliferation of T-lymphocyte that is in response to the antigenic and cytokine stimulation through a process that is different from other immunosuppressants. It can also inhibit the production of antibodies. By weakening the immune system, it helps the body accept the new organ after a kidney transplant.

How to use Rapamune

To initiate, read the medication guide or information leaflet that comes with this product. Do not use this oral drug if you have not fully understood the drug information and important instructions in the guide provided. If you need further medical advice on this treatment or have queries about this drug, you can ask your doctor or pharmacist.

Take this tablet orally. This is usually prescribed once a day. You will have to decide whether to take Rapamune with or without a meal and follow that every dose. Swallow the medication whole and drink a glass of water afterward. Dividing, crushing, or chewing the medication is not recommended.

Remember to take this immunosuppressant regularly to achieve optimum results. Make a dosing schedule. If you are prescribed cyclosporine, make sure to take this drug 4 hours after cyclosporine. Taking these medications at the same time could increase the levels of active ingredients in the system and cause problems to the kidney.

Do not alter your Rapamune dosage, as it is determined by your weight, medical condition, laboratory test results, and response to treatment. Additionally, do not stop taking Rapamune abruptly without the advice of your doctor.

Rapamune Side Effects

Common side effects:

• Nausea
• Vomiting
• Headache
• Joint pain
• Diarrhea
• Constipation
• Shaking
• Acne
• Insomnia or trouble sleeping

Mostly, the side effects brought about by this immunosuppressant are mild. If the adverse reactions get worse or take longer to resolve, you should consult your doctor or any healthcare professional. It is also highly necessary to report severe side effects, such as:

• Persistent nausea and vomiting
• Muscle cramps
• Dark urine
• Yellowish eyes and skin
• Bone pain
• Increased thirst
• Frequent urination
• Unusual tiredness
• Hearing problems
• Palpitation
• Bleeding
• Swelling of the extremities
• Mental or mood changes
• Swelling abdomen
• Chest pain
• Change in urine output
• Serious brain infection
• Infection symptoms (fever, chills, persistent sore throat)

This is not a complete or full list of Rapamune’s side effects.

Precautions

Before taking this immunosuppressant, make sure to disclose your entire medical history to your physician, especially high cholesterol or triglyceride levels, liver disease, cancer, or any infections. Some medical conditions may impact how your body will respond to this treatment. You must also talk about all the prescription drugs, nonprescription drugs, and supplements you are taking because of the possible drug interactions that they may have with this mTOR inhibitor.

Be watchful for an allergic reaction while on this treatment. Do not take this drug if you have a known allergy to sirolimus, temsirolimus, or any inactive ingredients each tablet may contain. Signs of hypersensitivity are severe dizziness, hives, swelling of the face and neck, breathing trouble, and skin rashes. You should seek emergency medical care if this occurs.

Since this is an immunosuppressant, you are more likely to get an infection when taking this drug. Always wash your hands properly and practice good hygiene every time. Avoid contact with people who have an infection or have recently received live vaccines. Patients taking this immunosuppressant must not also get vaccinated or immunized.

Avoid sun exposure while on Rapamune, for this drug may increase the risk of skin cancer. Limit your time under the sun and avoid prolonged, direct sun exposure. Indoor tanning must also be avoided. Wear protective clothing and apply sunblock cream when going outdoors.

Avoid eating grapefruit or drinking grapefruit juice. This fruit has a substance that could increase the Rapamune level in the system resulting in an increased risk of adverse effects.

This medication could pose undesirable effects to unborn babies and breastfed infants. Pregnant and breast feeding moms must not take this medication. Always remember that potential benefits must outweigh potential risks.

Frequently Asked Questions

Is Rapamune the same as rapamycin?

Yes, sirolimus is also known as rapamycin.

When is the best time to take Rapamune?

You may take this drug any time, but you may also ask your doctor for advice.

How long should I take Rapamune?

This medication is usually taken for 12 months or more, depending on your condition.

Does Rapamune cause seizures?

Seizures while taking this drug is rare. Thus, it must be reported immediately.

Can I purchase Rapamune online?

This oral medication can be purchased online by submitting a valid prescription.