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Daliresp (roflumilast) Indications

Daliresp, generic name roflumilast, is an oral prescription medication used for adults with severe chronic obstructive pulmonary disease (COPD). This medication prevents the worsening of COPD symptoms and decreases the number of flare-ups.

Daliresp is not a bronchodilator and it should not be used to relieve acute bronchospasms.

Daliresp is classified as a selective phosphodiesterase-4 inhibitor. The mechanism of action of this oral medication has not been fully defined, yet it is thought to work by reducing the release of inflammation mediators as it prevents tissue damage.

Daliresp (roflumilast) Uses and Dosage

Please read the medication information guide before taking Daliresp.

Always take Daliresp exactly as prescribed. The approved dosage is one tablet by mouth once daily, depending on the recommendation made by your physician. Create a dosing schedule and take it at the same time, as this tablet works best with equal intervals.

Daliresp should only be taken orally. You may take it with food or on an empty stomach. Swallow the entire film-coated tablet. Splitting it in half or chewing it is not recommended.

Daliresp (roflumilast) Side Effects

Some of the common side effects of Daliresp are:

• Nausea
• Diarrhea
• Headache
• Dizziness
• Abdominal pain
• Loss of appetite
• Weight loss

These adverse effects should be manageable, yet if they persist or worsen, then ask for medical assistance from your doctor.

Serious Side Effects

Some of the severe adverse effects of Daliresp are:

• Trouble sleeping
• Severe abdominal pain
• Persistent vomiting
• Urinary tract infection
• Muscle spasm
• Tremors
• Anxiety
• Depression

These adverse effects are uncommon, yet they should be reported to the doctor immediately if one or more occur.

Allergic Reactions

Avoid using Daliresp if you are allergic to roflumilast or any ingredients contained in the tablets. Seek emergency assistance if an allergy develops while using this prescription medication. Signs of an allergic reaction include:

• Itching
• Hives
• Rashes
• Swollen lymph nodes
• Severe dizziness
• Swelling of the face and neck
• Difficulty breathing
• Wheezing

Daliresp (roflumilast) Cautions

Daliresp may be contraindicated in patients with the following medical conditions:

• Liver disease
• Heart disease
• History of cancer
• Recent infections
• Immune system disorders
• Mood or mental disorders

Pregnant women should only use Daliresp if clearly necessary. The effects of this medication on the fetal development are still undetermined.

It is also not fully known if the contents of Daliresp can pass through breast milk. Know all the risks before taking this medication while breastfeeding.

Daliresp (roflumilast) Form and Strength

Daliresp prescription is available in the following forms and strengths:

• Daliresp, film-coated tablets
  • 500 mcg
• Roflumilast (generic), tablets
  • 500 mcg

FAQ

Is Daliresp a steroid?

Daliresp is not a steroid or a corticosteroid. It is classified as a phosphodiesterase-4 enzyme inhibitor.

What is the best time to take Daliresp?

There is no specific time to take Daliresp. It is probably best to take it in the morning as insomnia/trouble sleeping is an adverse effect.

Can prednisone and Daliresp be taken together?

Yes, you may take Daliresp and prednisone together. However, if Daliresp works sufficiently, it may be used without having to take prednisone.

Why does Daliresp cause weight loss?

Daliresp can lead to weight loss as it increases energy expenditure. In addition, it helps improve the metabolism of glucose.

Resources

https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/022522s003lbl.pdf

https://www.webmd.com/drugs/2/drug-155809/daliresp-oral/details