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Januvia (sitagliptin) Indications

Januvia, generic name sitagliptin, is prescribed to help lower blood sugar levels of adults who have type 2 diabetes mellitus (T2DM). This is taken along with proper diet and regular exercise.

By taking Januvia, complications of T2DM, such as kidney disease, eye impairment, nerve damage, cardiovascular diseases, and sexual dysfunction, may be prevented.

This prescription medication is not for type 1 diabetes and diabetic ketoacidosis.

Januvia is classified as a dipeptidyl peptidase-4 (DPP-4) inhibitor. It works by increasing the production of insulin. It also lowers the secretion of glucagon, which consequently decreases hepatic glucose production.

Januvia (sitagliptin) Uses and Dosage

Read the prescription guide before using Januvia.

Januvia is a once daily oral medication. Follow the dosage prescribed by your doctor and avoid changing your dose without seeking proper medical advice.

Swallow the Januvia tablet whole with a glass of water. The tablet must not be cut, chewed, or crushed. This medication can be taken with or without food.

Keep taking Januvia diabetes medication for as long as the doctor prescribes it.

Januvia (sitagliptin) Side Effects

Here are the common side effects of taking Januvia:

  • Stomach discomfort
  • Constipation
  • Diarrhea
  • Nausea
  • Headache
  • Stuffy nose

These adverse effects are supposed to be mild. If they worsen, you should consult your doctor.

Serious Side Effects

You should also report any severe undesirable effects that may occur while taking this prescription medication.

Among the serious side effects of Januvia are:

  • Unusual skin blisters
  • Joint pain
  • Unusual or sudden weight gain
  • Shortness of breath
  • Unusual tiredness
  • Swelling of the ankles and feet
  • Changes in urine output
  • Persistent nausea and vomiting
  • Severe abdominal pain
  • Loss of appetite
  • Low blood sugar
  • High blood sugar

Allergic Reactions

Those with known allergies to sitagliptin must not take Januvia. Note that inactive ingredients may also cause allergies.

Here are the common signs of an allergy:

  • Hives
  • Rashes
  • Itching
  • Swelling of the face and neck

With a severe allergy, you may also experience:

  • Severe dizziness
  • Trouble breathing
  • Wheezing

Januvia (sitagliptin) Cautions

This diabetes medication may be contraindicated for people with the following conditions:

  • Pancreatitis
  • Gallstones
  • Kidney disease
  • Heart failure

Reduce your alcohol intake while taking Januvia. Alcohol may cause hypoglycemia or low blood sugar levels.

Pregnancy may worsen symptoms of T2DM. Women who will get pregnant while using Januvia oral medication should consult the doctor for any changes in diabetes management. It is unknown if this particular medication is safe during pregnancy.

It is still undetermined whether Januvia can pass to breast milk. Talk to your doctor about the possible effects of this product on breastfed children.

Januvia (sitagliptin) Form and Strength

You can order Januvia prescription medication in the following forms and strengths:

  • Januvia tablets
    • 25 mg
    • 50 mg
    • 100 mg

FAQ

Is metformin and Januvia the same?

While these medications are both used to treat T2DM, they work differently. Metformin decreases the production of glucose, while Januvia medication increases the secretion of insulin.

Is it better to take Januvia in the morning or at night?

You may take this tablet in the morning or in the evening, based on your preference. For best results, take it at the same time every day.

Will Januvia make you gain weight?

Weight gain or even weight loss is not among the listed side effects of Januvia. If an unusual weight gain develops, this may indicate another underlying condition.

How long does it take for Januvia to lower blood sugar?

This medication may start to lower blood sugar within one to two weeks of use. Full beneficial effects are typically achieved after a few months of taking Januvia.

 

Resources

https://www.januvia.com/

https://www.webmd.com/drugs/2/drug-145704/januvia-oral/details

https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021995s019lbl.pdf

https://www.rxlist.com/januvia-drug.htm

Brand Name:

Januvia

Scientific Name:

Sitagliptin Malate, Sitagliptin Phosphate, Sitagliptin phosphate

Other Names:

Istavel, Januvia, Sitagliptin

Strength(s):

25mg, 50mg, 100mg

Quantities Available:

28, 84, 100, 168, 182

Formulation:

Film Coated Tablet, Tablet

Maple Leaf Medications has provided information from third parties intended to increase awareness and does not contain all the information about Januvia (Sitagliptin phosphate). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Januvia (Sitagliptin phosphate).