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What is Cymbalta? 

Cymbalta, with the generic name duloxetine HCl, is an oral medication used for major depressive disorder, generalized anxiety disorder, diabetic peripheral neuropathic pain, fibromyalgia, and chronic musculoskeletal pain. It also decreases nervousness and improves appetite, mood, sleep, and energy level. 

This selective serotonin and norepinephrine reuptake inhibitor (SNRI) has antidepressant, anxiolytic, and central pain inhibitory properties that may be due to the potentiation of noradrenergic and serotonergic activities in the central nervous system. This is available in Cymbalta 60 mg, 30 mg, and 20 mg capsule forms. 

How to use Cymbalta 

To begin, read and understand the medication information leaflet that comes with this drug. Never take this oral medication if you have not fully understood all the information in the guide. If you need further medical advice or have queries regarding this treatment, ask your doctor or pharmacist. 

Take this capsule orally. You can be taken with or without food. However, if you have nausea, it might help to take it with food. Do not split, cut, or chew the capsules to avoid releasing the active ingredients at once. Swallow the medication whole and drink a glass of water. 

Remember to rake this medication regularly and with a dosing schedule for best results. This oral capsule is usually taken once or twice a day – depending on the recommendation of your physician. Your Cymbalta dosage will depend on your age, medical condition, and response to treatment. Never alter your dosing or frequency. Moreover, do not stop taking this drug even if you feel better to avoid worsening conditions. 

Side effects 

Common side effects of Cymbalta: 

  • Nausea 
  • Drowsiness 
  • Dizziness 
  • Fatigue 
  • Dry mouth 
  • Loss of appetite 
  • Diarrhea 
  • Constipation 

In most cases, the adverse effects of this SNRI are mostly mild. If they persist or worsen, contact your doctor or any healthcare professionals as this may warrant a change in dosage or treatment. You also have to watch out for severe side effects, such as: 

  • Bleeding or easy bruising 
  • Confusion 
  • Muscle weakness 
  • Tremors 
  • Difficulty urinating 
  • Seizure 
  • Eye pain 
  • Widened pupils 
  • Signs of a liver problem (abdominal pain, persistent vomiting, yellowish skin and eyes, dark urine) 
  • Serotonin syndrome or toxicity (palpitations, hallucinations, loss of coordination, muscle twitching, agitation, unexplained fever) 

This is not a complete or full list of Cymbalta side effects. 

Precautions 

Before using this antidepressant, disclose your complete medical history to your physician, especially suicide attempts, psychiatric disorders, bleeding problems, high blood pressure, stomach problems, liver disease, kidney disease, glaucoma, and seizures. Some medical conditions may significantly affect how you will respond to treatment. In addition, tell your doctor about all the prescription drugs, nonprescription drugs, supplements, or herbal products you are taking as they might interact with duloxetine. 

Always watch out for an allergic reaction when taking this drug. Do not take this oral drug if you have a known allergy to duloxetine or other inactive ingredients that each capsule contains. Discontinue medication and seek emergency help when you develop signs of hypersensitivity response, such as skin rashes, swelling of the face, severe dizziness, hives, and difficulty breathing. 

Regularly check your blood sugar and blood pressure because they may be affected by this medication. If you develop hypertension or increase in blood sugar level, consult your doctor immediately. It may be necessary to adjust your other medications. 

Avoid alcoholic beverages and practice caution when doing activities that require alertness or clear vision, like using machinery or driving. This is because drowsiness, dizziness, and vision changes are among the side effects of this drug. 

Pregnant or breastfeeding women should avoid this SNRI. It is known to cause bleeding. It also passes into the breastmilk and could cause harm to a breastfed baby. 

Frequently Asked Questions 

What is this medication used for? 

Physicians prescribe Cymbalta for pain associated with peripheral neuropathy (nerve pain), depression, and anxiety. 

What are the signs of this medication withdrawal? 

Signs of withdrawal from this drug are irritability, vomiting, dizziness, prickling sensation, headaches, and nightmares. 

Is it okay to drink alcohol while on this medication? 

Cymbalta and alcohol may interact and cause worsening depression, increased risk of liver damage, and severe adverse reactions. 

Can Cymbalta cause weight gain? 

There is a link between Cymbalta & weight gain if used long-term. 

How much is Cymbalta? 

You may check the pricing of this product by clicking here.

Scientific Name:

Duloxetine, Duloxetine Hydrochloride

Formulation:

DR Capsule, DR Capsules, Delayed Release Capsule, Delayed Release Capsule (Enteric Coated)

Strength(s):

20mg, 30mg, 40mg, 60mg

Quantities Available:

28, 50, 56, 60, 84, 100, 168

Maple Leaf Medications has provided information from third parties intended to increase awareness and does not contain all the information about Cymbalta (Duloxetine). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Cymbalta (Duloxetine).